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130
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Sequence searches are routinely employed to detect and annotate related proteins. However, a rapid growth of databases necessitates a frequent repetition of sequence s...
133
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
137
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Microarray analysis allows the simultaneous measurement of thousands to millions of genes or sequences across tens to thousands of different samples. The analysis of t...
147
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: New systems biology studies require researchers to understand how interplay among myriads of biomolecular entities is orchestrated in order to achieve high-level cellu...
131
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: In DNA microarray gene expression profiling studies, a fundamental task is to extract statistically significant genes that meet certain research hypothesis. Currently,...