We describe an algorithm, IsoRank, for global alignment of two protein-protein interaction (PPI) networks. IsoRank aims to maximize the overall match between the two networks; in c...
As the amount of data being generated in biology has increased, a major challenge has been how to store and represent this data in a way that makes it easily accessible to researc...
Michael Backhaus, Janet Kelso, Joshua Bacher, Hein...
Background: Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a u...
Background: One type of DNA microarray experiment is discovery of gene expression patterns for a cell line undergoing a biological process over a series of time points. Two import...
Abstract. Meaningful notions of distance between planar shapes typically involve the computation of a correspondence between points on one shape and points on the other. To determi...