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» The Equivalence between Biology and Computation
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RECOMB
2007
Springer
16 years 1 months ago
Free Energy Estimates of All-Atom Protein Structures Using Generalized Belief Propagation
We present a technique for approximating the free energy of protein structures using Generalized Belief Propagation (GBP). The accuracy and utility of these estimates are then demo...
Hetunandan Kamisetty, Eric P. Xing, Christopher Ja...
RECOMB
2006
Springer
16 years 1 months ago
A Study of Accessible Motifs and RNA Folding Complexity
mRNA molecules are folded in the cells and therefore many of their substrings may actually be inaccessible to protein and microRNA binding. The need to apply an accessability crite...
Ydo Wexler, Chaya Ben-Zaken Zilberstein, Michal Zi...
RECOMB
2005
Springer
16 years 1 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli
109
Voted
DATE
2009
IEEE
159views Hardware» more  DATE 2009»
15 years 8 months ago
Design and implementation of a database filter for BLAST acceleration
— BLAST is a very popular Computational Biology algorithm. Since it is computationally expensive it is a natural target for acceleration research, and many reconfigurable archite...
Panagiotis Afratis, Constantinos Galanakis, Euripi...
BMCBI
2010
156views more  BMCBI 2010»
15 years 1 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...