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» The Equivalence between Biology and Computation
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BMCBI
2007
216views more  BMCBI 2007»
14 years 12 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
GECCO
2007
Springer
165views Optimization» more  GECCO 2007»
15 years 6 months ago
Peptide detectability following ESI mass spectrometry: prediction using genetic programming
The accurate quantification of proteins is important in several areas of cell biology, biotechnology and medicine. Both relative and absolute quantification of proteins is often d...
David C. Wedge, Simon J. Gaskell, Simon J. Hubbard...
BMCBI
2007
153views more  BMCBI 2007»
14 years 12 months ago
An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network
Background: Alternative representations of biochemical networks emphasise different aspects of the data and contribute to the understanding of complex biological systems. In this ...
Brian J. Holden, John W. Pinney, Simon C. Lovell, ...
BMCBI
2006
153views more  BMCBI 2006»
14 years 12 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
PODS
2008
ACM
211views Database» more  PODS 2008»
15 years 12 months ago
The power of two min-hashes for similarity search among hierarchical data objects
In this study we propose sketching algorithms for computing similarities between hierarchical data. Specifically, we look at data objects that are represented using leaf-labeled t...
Sreenivas Gollapudi, Rina Panigrahy