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104
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2004
Springer
16 years 29 days ago
2004
Springer
We study a situation that arises in the somatic evolution of cancer. Consider a finite population of replicating cells and a sequence of mutations: type 0 can mutate to type 1, wh...
70
Voted
RECOMB
2003
Springer
16 years 29 days ago
2003
Springer
We study a design and optimization problem that occurs, for example, when single nucleotide polymorphisms (SNPs) are to be genotyped using a universal DNA tag array. The problem o...
99
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RECOMB
2003
Springer
16 years 29 days ago
2003
Springer
It is shown that structural similarity between proteins can be decided well with much less information than what is used in common similarity measures. The full C representation c...
90
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RECOMB
2002
Springer
16 years 29 days ago
2002
Springer
We develop techniques to estimate the statistical significance of gap-free alignments between two genomic DNA sequences, using human-mouse alignments as an example. The sequences ...
94
Voted
RECOMB
2009
Springer
15 years 7 months ago
2009
Springer
Abstract. There have been many widely used genome rearrangement models, such as reversals, HannenhalliPevzner, and double-cut and join. Though each one can be precisely defined, t...