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» The Equivalence between Biology and Computation
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88
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DNA
2009
Springer
185views Bioinformatics» more  DNA 2009»
15 years 7 months ago
NP-Completeness of the Direct Energy Barrier Problem without Pseudoknots
Knowledge of energy barriers between pairs of secondary structures for a given DNA or RNA molecule is useful, both in understanding RNA function in biological settings and in desig...
Ján Manuch, Chris Thachuk, Ladislav Stacho,...
120
Voted
RECOMB
2000
Springer
15 years 4 months ago
A compression algorithm for DNA sequences and its applications in genome comparison
We present a lossless compression algorithm, GenCompress, for genetic sequences, based on searching for approximate repeats. Our algorithm achieves the best compression ratios for...
Xin Chen, Sam Kwong, Ming Li
109
Voted
ASM
2008
ASM
15 years 2 months ago
The High Road to Formal Validation:
Abstract. In this paper we examine the difference between model checking high-level and low-level models. In particular, we compare the ProB model checker for the B-method and the ...
Michael Leuschel
102
Voted
ASM
2008
ASM
15 years 2 months ago
Model Based Refinement and the Tools of Tomorrow
The ingredients of typical model based development via refinement are re-examined, and some well known frameworks are reviewed in that light, drawing out commonalities and differen...
Richard Banach
90
Voted
ISMB
1998
15 years 2 months ago
Phylogenetic Inference in Protein Superfamilies: Analysis of SH2 Domains
This workfocuses on the inference of evolutionary relationships in protein superfamilies, and the uses of these relationships to identify keypositions in the structure, to infer a...
Kimmen Sjölander