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» The Expression Problem Revisited
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CORR
2010
Springer
153views Education» more  CORR 2010»
15 years 6 months ago
The Complexity of Causality and Responsibility for Query Answers and non-Answers
An answer to a query has a well-defined lineage expression (alternatively called how-provenance) that explains how the answer was derived. Recent work has also shown how to comput...
Alexandra Meliou, Wolfgang Gatterbauer, Katherine ...
BMCBI
2006
127views more  BMCBI 2006»
15 years 6 months ago
Automatic discovery of cross-family sequence features associated with protein function
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
Markus Brameier, Josien Haan, Andrea Krings, Rober...
BMCBI
2006
145views more  BMCBI 2006»
15 years 6 months ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
BMCBI
2006
175views more  BMCBI 2006»
15 years 6 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
BMCBI
2006
104views more  BMCBI 2006»
15 years 6 months ago
Semi-supervised discovery of differential genes
Background: Various statistical scores have been proposed for evaluating the significance of genes that may exhibit differential expression between two or more controlled conditio...
Shigeyuki Oba, Shin Ishii