Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Background: The accurate prediction of a comprehensive set of messenger RNAs (targets) regulated by animal microRNAs (miRNAs) remains an open problem. In particular, the predictio...
Background: Numerous feature selection methods have been applied to the identification of differentially expressed genes in microarray data. These include simple fold change, clas...
Background: In this study, we present a robust and reliable computational method for tag-togene assignment in serial analysis of gene expression (SAGE). The method relies on curre...
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...