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138
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BMCBI
2010
15 years 4 months ago
2010
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
124
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BMCBI
2010
15 years 4 months ago
2010
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
138
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BMCBI
2008
15 years 4 months ago
2008
Motivation: In the last years more than 20 vertebrate genomes have been sequenced, and the rate at which genomic DNA information becomes available is rapidly accelerating. Gene du...
127
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BMCBI
2008
15 years 4 months ago
2008
Background: DNA microarrays contain thousands of different probe sequences represented on their surface. These are designed in such a way that potential cross-hybridization reacti...
148
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BMCBI
2008
15 years 4 months ago
2008
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...