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» The Frobenius Problem and Its Generalizations
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BMCBI
2010
150views more  BMCBI 2010»
14 years 12 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BMCBI
2010
183views more  BMCBI 2010»
14 years 12 months ago
SING: Subgraph search In Non-homogeneous Graphs
Background: Finding the subgraphs of a graph database that are isomorphic to a given query graph has practical applications in several fields, from cheminformatics to image unders...
Raffaele Di Natale, Alfredo Ferro, Rosalba Giugno,...
BMCBI
2010
105views more  BMCBI 2010»
14 years 12 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2010
117views more  BMCBI 2010»
14 years 12 months ago
Automatic, context-specific generation of Gene Ontology slims
Background: The use of ontologies to control vocabulary and structure annotation has added value to genomescale data, and contributed to the capture and re-use of knowledge across...
Melissa J. Davis, Muhammad Shoaib B. Sehgal, Mark ...
CORR
2010
Springer
172views Education» more  CORR 2010»
14 years 12 months ago
The MUSIC Algorithm for Sparse Objects: A Compressed Sensing Analysis
The MUSIC algorithm, and its extension for imaging sparse extended objects, with noisy data is analyzed by compressed sensing (CS) techniques. A thresholding rule is developed to a...
Albert Fannjiang