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» The Future Is Not Assured - But It Should Be
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ASE
2010
86views more  ASE 2010»
15 years 1 months ago
Stable rankings for different effort models
There exists a large and growing number of proposed estimation methods but little conclusive evidence ranking one method over another. Prior effort estimation studies suffered fro...
Tim Menzies, Omid Jalali, Jairus Hihn, Daniel Bake...
BMCBI
2008
111views more  BMCBI 2008»
15 years 1 months ago
Comparative optimism in models involving both classical clinical and gene expression information
Background: In cancer research, most clinical variables have already been investigated and are now well established. The use of transcriptomic variables has raised two problems: r...
Caroline Truntzer, Delphine Maucort-Boulch, Pascal...
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BMCBI
2008
94views more  BMCBI 2008»
15 years 1 months ago
A comprehensive re-analysis of the Golden Spike data: Towards a benchmark for differential expression methods
Background: The Golden Spike data set has been used to validate a number of methods for summarizing Affymetrix data sets, sometimes with seemingly contradictory results. Much less...
Richard D. Pearson
BMCBI
2008
158views more  BMCBI 2008»
15 years 1 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
BMCBI
2008
106views more  BMCBI 2008»
15 years 1 months ago
Ontology Design Patterns for bio-ontologies: a case study on the Cell Cycle Ontology
Background: Bio-ontologies are key elements of knowledge management in bioinformatics. Rich and rigorous bio-ontologies should represent biological knowledge with high fidelity an...
Mikel Egaña Aranguren, Erick Antezana, Mart...