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BMCBI
2006
135views more  BMCBI 2006»
14 years 12 months ago
TF Target Mapper: A BLAST search tool for the identification of Transcription Factor target genes
Background: In the current era of high throughput genomics a major challenge is the genome-wide identification of target genes for specific transcription factors. Chromatin immuno...
Sebastiaan Horsman, Michael J. Moorhouse, Victor C...
BMCBI
2008
120views more  BMCBI 2008»
14 years 12 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2006
203views more  BMCBI 2006»
14 years 12 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...
BMCBI
2007
99views more  BMCBI 2007»
14 years 12 months ago
Towards validating the hypothesis of phylogenetic profiling
Background: As the number of fully sequenced genome increases, the need is greater for bioinformatics to predict or annotate genes of a newly sequenced genome. Ever since Eisenber...
Raja Loganantharaj, Mazen Atwi
BIBE
2004
IEEE
128views Bioinformatics» more  BIBE 2004»
15 years 3 months ago
Towards a Proteomics Meta-Classification
There is a recognized need for a meta-classification that can serve as a foundation for more refined ontologies in the field of proteomics. Standard data sources classify proteins...
Anand Kumar, Barry Smith