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107
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BMCBI
2010
14 years 5 months ago
2010
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
104
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BMCBI
2010
14 years 5 months ago
2010
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
BMCBI
2010
14 years 5 months ago
2010
Background: Quantification of different types of cells is often needed for analysis of histological images. In our project, we compute the relative number of proliferating hepatoc...
119
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BMCBI
2010
14 years 5 months ago
2010
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
107
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BMCBI
2011
14 years 5 months ago
2011
Background: With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these mol...