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BMCBI
2008
139views more  BMCBI 2008»
14 years 10 months ago
A topological transformation in evolutionary tree search methods based on maximum likelihood combining p-ECR and neighbor joinin
Background: Inference of evolutionary trees using the maximum likelihood principle is NP-hard. Therefore, all practical methods rely on heuristics. The topological transformations...
Maozu Guo, Jian-Fu Li, Yang Liu
BMCBI
2006
82views more  BMCBI 2006»
14 years 10 months ago
Profiling alternatively spliced mRNA isoforms for prostate cancer classification
Background: Prostate cancer is one of the leading causes of cancer illness and death among men in the United States and world wide. There is an urgent need to discover good biomar...
Chaolin Zhang, Hai-Ri Li, Jian-Bing Fan, Jessica W...
BMCBI
2006
72views more  BMCBI 2006»
14 years 10 months ago
Selecting effective siRNA sequences by using radial basis function network and decision tree learning
Background: Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are o...
Shigeru Takasaki, Yoshihiro Kawamura, Akihiko Kona...
IANDC
2008
141views more  IANDC 2008»
14 years 10 months ago
Graph connectivity, partial words, and a theorem of Fine and Wilf
The problem of computing periods in words, or finite sequences of symbols from a finite alphabet, has important applications in several areas including data compression, string se...
Francine Blanchet-Sadri, Deepak Bal, Gautam Sisodi...
BMCBI
2006
122views more  BMCBI 2006»
14 years 10 months ago
PET-Tool: a software suite for comprehensive processing and managing of Paired-End diTag (PET) sequence data
Background: We recently developed the Paired End diTag (PET) strategy for efficient characterization of mammalian transcriptomes and genomes. The paired end nature of short PET se...
Kuo Ping Chiu, Chee-Hong Wong, Qiongyu Chen, Prami...
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