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HCW
1998
IEEE
15 years 5 months ago
Implementing Distributed Synthetic Forces Simulations in Metacomputing Environments
A distributed, parallel implementation of the widely used Modular Semi-Automated Forces ModSAF Distributed Interactive Simulation DIS is presented, with Scalable Parallel Processo...
Sharon Brunett, Dan Davis, Thomas Gottschalk, Paul...
RECOMB
2010
Springer
15 years 3 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
BMCBI
2007
105views more  BMCBI 2007»
15 years 1 months ago
Generating confidence intervals on biological networks
Background: In the analysis of networks we frequently require the statistical significance of some network statistic, such as measures of similarity for the properties of interact...
Thomas Thorne, Michael P. H. Stumpf
BMCBI
2008
131views more  BMCBI 2008»
15 years 1 months ago
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
Min Li, Jianer Chen, Jianxin Wang, Bin Hu, Gang Ch...
BMCBI
2006
103views more  BMCBI 2006»
15 years 1 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...