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» The Importance of Symmetric Representation
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BMCBI
2010
137views more  BMCBI 2010»
14 years 10 months ago
TreeGraph 2: Combining and visualizing evidence from different phylogenetic analyses
Background: Today it is common to apply multiple potentially conflicting data sources to a given phylogenetic problem. At the same time, several different inference techniques are...
Ben C. Stöver, Kai F. Müller
BMCBI
2010
120views more  BMCBI 2010»
14 years 10 months ago
Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
Kang Ning, Hoong Kee Ng, Sriganesh Srihari, Hon Wa...
BMCBI
2007
134views more  BMCBI 2007»
14 years 10 months ago
Benchmarking natural-language parsers for biological applications using dependency graphs
Background: Interest is growing in the application of syntactic parsers to natural language processing problems in biology, but assessing their performance is difficult because di...
Andrew B. Clegg, Adrian J. Shepherd
BMCBI
2007
147views more  BMCBI 2007»
14 years 10 months ago
Hon-yaku: a biology-driven Bayesian methodology for identifying translation initiation sites in prokaryotes
Background: Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remain...
Yuko Makita, Michiel J. L. de Hoon, Antoine Danchi...
BMCBI
2010
147views more  BMCBI 2010»
14 years 10 months ago
baySeq: Empirical Bayesian methods for identifying differential expression in sequence count data
Background: High throughput sequencing has become an important technology for studying expression levels in many types of genomic, and particularly transcriptomic, data. One key w...
Thomas J. Hardcastle, Krystyna A. Kelly