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» The Inference Based on Molecular Computing
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ISMB
1998
15 years 9 days ago
A Hidden Markov Model for Predicting Transmembrane Helices in Protein Sequences
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
Erik L. L. Sonnhammer, Gunnar von Heijne, Anders K...
DAC
2010
ACM
14 years 11 months ago
A correlation-based design space exploration methodology for multi-processor systems-on-chip
Given the increasing complexity of multi-processor systems-onchip, a wide range of parameters must be tuned to find the best trade-offs in terms of the selected system figures of ...
Giovanni Mariani, Aleksandar Brankovic, Gianluca P...
IJMMS
2007
163views more  IJMMS 2007»
14 years 11 months ago
Beyond ontologies: Toward situated representations of scientific knowledge
: In information systems that support knowledge-discovery applications such as scientific exploration, reliance on highly structured ontologies as data-organization aids can be lim...
William Pike, Mark Gahegan
BMCBI
2005
212views more  BMCBI 2005»
14 years 11 months ago
PAGE: Parametric Analysis of Gene Set Enrichment
Background: Gene set enrichment analysis (GSEA) is a microarray data analysis method that uses predefined gene sets and ranks of genes to identify significant biological changes i...
Seon-Young Kim, David J. Volsky
112
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BMCBI
2005
122views more  BMCBI 2005»
14 years 11 months ago
Bayesian coestimation of phylogeny and sequence alignment
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
Gerton Lunter, István Miklós, Alexei...