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» The Inference Problem: A Survey
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BMCBI
2010
118views more  BMCBI 2010»
15 years 6 months ago
From learning taxonomies to phylogenetic learning: Integration of 16S rRNA gene data into FAME-based bacterial classification
Background: Machine learning techniques have shown to improve bacterial species classification based on fatty acid methyl ester (FAME) data. Nonetheless, FAME analysis has a limit...
Bram Slabbinck, Willem Waegeman, Peter Dawyndt, Pa...
BMCBI
2006
147views more  BMCBI 2006»
15 years 6 months ago
A case study in pathway knowledgebase verification
Background: Biological databases and pathway knowledgebases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we...
Stephen A. Racunas, Nigam Shah, Nina V. Fedoroff
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BMCBI
2006
126views more  BMCBI 2006»
15 years 6 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
NETWORK
2007
167views more  NETWORK 2007»
15 years 5 months ago
Sensor Localization under Limited Measurement Capabilities
If we abstract a sensor network as a network graph consisting of vertices and edges, where vertices represent sensor nodes and edges represent distance measurements between neighbo...
Chen Wang, Li Xiao