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BIOINFORMATICS
2010
14 years 9 months ago
2010
Motivation: The fruit fly (Drosophila melanogaster) is a commonly used model organism in biology. We are currently building a 3D digital atlas of the fruit fly larval nervous syst...
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BMCBI
2010
14 years 9 months ago
2010
Background: Minimotifs are short peptide sequences within one protein, which are recognized by other proteins or molecules. While there are now several minimotif databases, they a...
BMCBI
2010
14 years 9 months ago
2010
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
BMCBI
2010
14 years 9 months ago
2010
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
BMCBI
2010
2010
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
14 years 9 months ago
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...