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» The Motif Tracking Algorithm
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104
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BMCBI
2006
113views more  BMCBI 2006»
15 years 15 days ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
106
Voted
COCOON
2008
Springer
15 years 2 months ago
Quasi-bicliques: Complexity and Binding Pairs
Abstract. Protein-protein interactions (PPIs) are one of the most important mechanisms in cellular processes. To model protein interaction sites, recent studies have suggested to f...
Xiaowen Liu, Jinyan Li, Lusheng Wang
BMCBI
2006
87views more  BMCBI 2006»
15 years 15 days ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
BMCBI
2007
86views more  BMCBI 2007»
15 years 17 days ago
Detecting microsatellites within genomes: significant variation among algorithms
Background: Microsatellites are short, tandemly-repeated DNA sequences which are widely distributed among genomes. Their structure, role and evolution can be analyzed based on exh...
Sébastien Leclercq, Eric Rivals, Philippe J...
105
Voted
GECCO
2007
Springer
158views Optimization» more  GECCO 2007»
15 years 6 months ago
A novel generative encoding for exploiting neural network sensor and output geometry
A significant problem for evolving artificial neural networks is that the physical arrangement of sensors and effectors is invisible to the evolutionary algorithm. For example,...
David B. D'Ambrosio, Kenneth O. Stanley