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AE
2005
Springer
15 years 3 months ago
Incorporating Knowledge of Secondary Structures in a L-System-Based Encoding for Protein Folding
An encoding scheme for protein folding on lattice models, inspired by parametric L-systems, was proposed. The encoding incorporates problem domain knowledge in the form of predesig...
Gabriela Ochoa, Gabi Escuela, Natalio Krasnogor
SDM
2008
SIAM
112views Data Mining» more  SDM 2008»
14 years 11 months ago
A pattern mining approach toward discovering generalized sequence signatures
Typically, sequence signatures, such as motifs and domains, are assumed to be localized in one region of a sequence or are derived as combinations of the former. We generalize the...
Dietmar H. Dorr, Anne Denton
ISMB
2000
14 years 11 months ago
A Statistical Method for Finding Transcription Factor Binding Sites
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
Saurabh Sinha, Martin Tompa
JCB
2008
75views more  JCB 2008»
14 years 10 months ago
New, Improved, and Practical k-Stem Sequence Similarity Measures for Probe Design
We define new measures of sequence similarity for oligonucleotide probe design. These new measures incorporate the nearest neighbor k-stem motifs in their definition, but can be e...
Anthony J. Macula, Alexander Schliep, Morgan A. Bi...
NAR
2006
107views more  NAR 2006»
14 years 9 months ago
CorGen - measuring and generating long-range correlations for DNA sequence analysis
CorGen is a web server that measures long-range correlations in the base composition of DNA and generates random sequences with the same correlation parameters. Long-range correla...
Philipp W. Messer, Peter F. Arndt