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    BMCBI
    2006
    127views more  BMCBI 2006»
    Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
    14 years 9 months ago
    Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
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    Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
    Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
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    BMCBI
    2006
    119views more  BMCBI 2006»
    Hidden Markov Model Variants and their Application
    14 years 9 months ago
    Hidden Markov Model Variants and their Application
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    Markov statistical methods may make it possible to develop an unsupervised learning process that can automatically identify genomic structure in prokaryotes in a comprehensive way...
    Stephen Winters-Hilt
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    BMCBI
    2006
    161views more  BMCBI 2006»
    Comparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome
    14 years 9 months ago
    Comparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome
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    Background: Automatic annotation of sequenced eukaryotic genomes integrates a combination of methodologies such as ab-initio methods and alignment of homologous genes and/or prote...
    Alan Christoffels, Richard Bartfai, Hamsa Srinivas...
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    BMCBI
    2006
    111views more  BMCBI 2006»
    Using ESTs to improve the accuracy of de novo gene prediction
    14 years 9 months ago
    Using ESTs to improve the accuracy of de novo gene prediction
    Download  mblab.wustl.edu
    Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
    Chaochun Wei, Michael R. Brent
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    BMCBI
    2006
    108views more  BMCBI 2006»
    Gene function classification using Bayesian models with hierarchy-based priors
    14 years 9 months ago
    Gene function classification using Bayesian models with hierarchy-based priors
    Download  www.cs.utoronto.ca
    We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
    Babak Shahbaba, Radford M. Neal
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