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BMCBI
2010
151views more  BMCBI 2010»
14 years 10 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...
BMCBI
2008
90views more  BMCBI 2008»
14 years 10 months ago
Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expe
Background: Many common disorders have multiple genetic components which convey increased susceptibility. SNPs have been used to identify genetic components which are associated w...
Don L. Armstrong, Chaim O. Jacob, Raphael Zidovetz...
BMCBI
2008
175views more  BMCBI 2008»
14 years 10 months ago
Synonym set extraction from the biomedical literature by lexical pattern discovery
Background: Although there are a large number of thesauri for the biomedical domain many of them lack coverage in terms and their variant forms. Automatic thesaurus construction b...
John McCrae, Nigel Collier
BMCBI
2008
136views more  BMCBI 2008»
14 years 10 months ago
GPAT: Retrieval of genomic annotation from large genomic position datasets
Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
Arnaud Krebs, Mattia Frontini, Làszlò...
BMCBI
2008
77views more  BMCBI 2008»
14 years 10 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
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