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ALMOB
2008
85views more  ALMOB 2008»
14 years 12 months ago
Noisy: Identification of problematic columns in multiple sequence alignments
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
Andreas W. M. Dress, Christoph Flamm, Guido Fritzs...
84
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ALMOB
2008
124views more  ALMOB 2008»
14 years 12 months ago
A scoring matrix approach to detecting miRNA target sites
Background: Experimental identification of microRNA (miRNA) targets is a difficult and time consuming process. As a consequence several computational prediction methods have been ...
Simon Moxon, Vincent Moulton, Jan T. Kim
97
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ALIFE
2007
14 years 12 months ago
Synchronization Phenomena in Surface-Reaction Models of Protocells
A class of generic models of protocells is introduced, which are inspired by the “Los Alamos bug” is but which, due to their abstraction level, can be applied to a wider set o...
Roberto Serra, Timoteo Carletti, Irene Poli
ALMOB
2007
155views more  ALMOB 2007»
14 years 12 months ago
Finding coevolving amino acid residues using row and column weighting of mutual information and multi-dimensional amino acid rep
Background: Some amino acid residues functionally interact with each other. This interaction will result in an evolutionary co-variation between these residues – coevolution. Ou...
Rodrigo Gouveia-Oliveira, Anders Gorm Pedersen
BIODATAMINING
2008
96views more  BIODATAMINING 2008»
14 years 12 months ago
Fast approximate hierarchical clustering using similarity heuristics
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Meelis Kull, Jaak Vilo
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