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109
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ALIFE
2006
15 years 1 months ago
The Origin of the Eukaryotic Cell Based on Conservation of Existing Interfaces
Current theories about the origin of the eukaryotic cell all assume that during evolution a prokaryotic cell acquired a nucleus. Here, it is shown that a scenario in which the nucl...
Albert D. G. de Roos
122
Voted
BMCBI
2004
174views more  BMCBI 2004»
15 years 28 days ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
111
Voted
CSB
2005
IEEE
133views Bioinformatics» more  CSB 2005»
15 years 6 months ago
Creating a Protein Ontology Resource
Protein Data Integration approaches at the moment considers data sources as data repositories, but not as applications; which in turn may embody complex interactions with other da...
Amandeep S. Sidhu, Tharam S. Dillon, Elizabeth Cha...
124
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BMCBI
2011
14 years 8 months ago
OrthoInspector: comprehensive orthology analysis and visual exploration
Background: The accurate determination of orthology and inparalogy relationships is essential for comparative sequence analysis, functional gene annotation and evolutionary studie...
Benjamin Linard, Julie D. Thompson, Olivier Poch, ...
156
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NAR
2007
121views more  NAR 2007»
15 years 17 days ago
WormBase: new content and better access
WormBase (http://wormbase.org), a model organism database for Caenorhabditis elegans and other related nematodes, continues to evolve and expand. Over the past year WormBase has a...
Tamberlyn Bieri, Darin Blasiar, Philip Ozersky, Ig...