We propose an unsupervised methodology using independent component analysis (ICA) to cluster genes from DNA microarray data. Based on an ICA mixture model of genomic expression pa...
Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
In recent years, the rapid development of DNA Microarray technology has made it possible for scientists to monitor the expression level of thousands of genes in a single experiment...
Background: In microarray experiments the numbers of replicates are often limited due to factors such as cost, availability of sample or poor hybridization. There are currently fe...
The immensevolumeof data resulting from DNAmicroarray experiments, accompaniedby an increase in the numberof publications discussing gene-related discoveries, presents a majordata...
Hagit Shatkay, Stephen Edwards, W. John Wilbur, Ma...