The representation of a genome by oligonucleotide probes is a prerequisite for the analysis of many of its basic properties, such as transcription factor binding sites, chromosomal...
Background: The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. Tools such...
Barry Zeeberg, Hongfang Liu, Ari B. Kahn, Martin E...
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
—In this paper, we have modified a constrained clustering algorithm to perform exploratory analysis on gene expression data using prior knowledge presented in the form of constr...
Erliang Zeng, Chengyong Yang, Tao Li, Giri Narasim...
Background: Mean-based clustering algorithms such as bisecting k-means generally lack robustness. Although componentwise median is a more robust alternative, it can be a poor cent...
Yuanyuan Ding, Xin Dang, Hanxiang Peng, Dawn Wilki...