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» The ParTriCluster Algorithm for Gene Expression Analysis
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TCBB
2008
113views more  TCBB 2008»
15 years 10 days ago
Efficient Algorithms for the Computational Design of Optimal Tiling Arrays
The representation of a genome by oligonucleotide probes is a prerequisite for the analysis of many of its basic properties, such as transcription factor binding sites, chromosomal...
Alexander Schliep, Roland Krause
121
Voted
BMCBI
2011
14 years 7 months ago
RedundancyMiner: De-replication of redundant GO categories in microarray and proteomics analysis
Background: The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. Tools such...
Barry Zeeberg, Hongfang Liu, Ari B. Kahn, Martin E...
126
Voted
BMCBI
2006
122views more  BMCBI 2006»
15 years 15 days ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BIBE
2007
IEEE
151views Bioinformatics» more  BIBE 2007»
15 years 2 months ago
On the Effectiveness of Constraints Sets in Clustering Genes
—In this paper, we have modified a constrained clustering algorithm to perform exploratory analysis on gene expression data using prior knowledge presented in the form of constr...
Erliang Zeng, Chengyong Yang, Tao Li, Giri Narasim...
116
Voted
BMCBI
2007
123views more  BMCBI 2007»
15 years 13 days ago
Robust clustering in high dimensional data using statistical depths
Background: Mean-based clustering algorithms such as bisecting k-means generally lack robustness. Although componentwise median is a more robust alternative, it can be a poor cent...
Yuanyuan Ding, Xin Dang, Hanxiang Peng, Dawn Wilki...