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RECOMB
2005
Springer
16 years 1 months ago
The Pathalyzer: A Tool for Analysis of Signal Transduction Pathways
Abstract. The Pathalyzer is a program for analyzing large-scale signal transduction networks. Reactions and their substrates and products are represented as transitions and places ...
David L. Dill, Merrill Knapp, Pamela Gage, Carolyn...
121
Voted
BMCBI
2005
114views more  BMCBI 2005»
15 years 29 days ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
131
Voted
CMSB
2009
Springer
15 years 4 months ago
On the Use of Stochastic Petri Nets in the Analysis of Signal Transduction Pathways for Angiogenesis Process
In this paper we consider the modeling of a selected portion of signal transduction events involved in the angiogenesis process. The detailed model of this process contains a large...
Lucia Napione, Daniele Manini, Francesca Cordero, ...
129
Voted
BMCBI
2011
14 years 8 months ago
Context-dependent transcriptional regulations between signal transduction pathways
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
Sohyun Hwang, Sangwoo Kim, Heesung Shin, Doheon Le...
124
Voted
BMCBI
2006
205views more  BMCBI 2006»
15 years 1 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch