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BMCBI
2007
121views more  BMCBI 2007»
15 years 2 months ago
Predicting zinc binding at the proteome level
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...
BMCBI
2007
146views more  BMCBI 2007»
15 years 2 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2008
133views more  BMCBI 2008»
15 years 2 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...
BMCBI
2007
160views more  BMCBI 2007»
15 years 2 months ago
Identifying protein complexes directly from high-throughput TAP data with Markov random fields
Background: Predicting protein complexes from experimental data remains a challenge due to limited resolution and stochastic errors of high-throughput methods. Current algorithms ...
Wasinee Rungsarityotin, Roland Krause, Arno Sch&ou...
BMCBI
2010
146views more  BMCBI 2010»
15 years 2 months ago
Booly: a new data integration platform
Background: Data integration is an escalating problem in bioinformatics. We have developed a web tool and warehousing system, Booly, that features a simple yet flexible data model...
Long H. Do, Francisco F. Esteves, Harvey J. Karten...
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