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BMCBI
2010
14 years 9 months ago
2010
Background: Sub-cellular structures interact in numerous direct and indirect ways in order to fulfill cellular functions. While direct molecular interactions crucially depend on s...
BMCBI
2008
14 years 9 months ago
2008
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
BMCBI
2010
14 years 9 months ago
2010
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
BMCBI
2010
14 years 9 months ago
2010
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
BMCBI
2010
2010
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
14 years 9 months ago
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...