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105
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BMCBI
2004
15 years 17 days ago
2004
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
131
Voted
BMCBI
2010
15 years 24 days ago
2010
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
96
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BMCBI
2010
2010
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
15 years 24 days ago
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
121
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BMCBI
2008
15 years 24 days ago
2008
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
BMCBI
2007
15 years 24 days ago
2007
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...