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BMCBI
2005
113views more  BMCBI 2005»
15 years 18 days ago
Alternative splicing and protein function
Background: Alternative splicing is a major mechanism of generating protein diversity in higher eukaryotes. Although at least half, and probably more, of mammalian genes are alter...
A. D. Neverov, Irena I. Artamonova, Ramil N. Nurtd...
NAR
2010
148views more  NAR 2010»
14 years 7 months ago
SIMAP - a comprehensive database of pre-calculated protein sequence similarities, domains, annotations and clusters
The prediction of protein function as well as the reconstruction of evolutionary genesis employing sequence comparison at large is still the most powerful tool in sequence analysi...
Thomas Rattei, Patrick Tischler, Stefan Götz,...
85
Voted
BMCBI
2006
114views more  BMCBI 2006»
15 years 22 days ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
105
Voted
BMCBI
2010
151views more  BMCBI 2010»
15 years 24 days ago
Data reduction for spectral clustering to analyze high throughput flow cytometry data
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...
91
Voted
ESCIENCE
2007
IEEE
15 years 7 months ago
eResearch Solutions for High Throughput Structural Biology
Structural biology research places significant demands upon computing and informatics infrastructure. Protein production, crystallization and X-ray data collection require solutio...
Noel G. Faux, Anthony Beitz, Mark A. Bate, Abdulla...