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137
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BMCBI
2007
166views more  BMCBI 2007»
15 years 28 days ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2007
127views more  BMCBI 2007»
15 years 28 days ago
Characterization of protein-interaction networks in tumors
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
Alexander Platzer, Paul Perco, Arno Lukas, Bernd M...
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
15 years 26 days ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
108
Voted
BMCBI
2008
158views more  BMCBI 2008»
15 years 28 days ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
WWW
2008
ACM
16 years 1 months ago
Online change detection in individual web user behaviour
Based on our field studies and consultations with field experts, we identified three main problems that are of key importance to online web personalization and customer relationsh...
Peter Hofgesang, Jan Peter Patist