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98
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RECOMB
2002
Springer
16 years 1 months ago
Probabilistic hierarchical clustering for biological data
Biological data, such as gene expression profiles or protein sequences, is often organized in a hierarchy of classes, where the instances assigned to "nearby" classes in...
Eran Segal, Daphne Koller
CSB
2005
IEEE
210views Bioinformatics» more  CSB 2005»
15 years 6 months ago
Problem Solving Environment Approach to Integrating Diverse Biological Data Sources
Scientists face an ever-increasing challenge in investigating biological systems with high throughput experimental methods such as mass spectrometry and gene arrays because of the...
Eric G. Stephan, Kyle R. Klicker, Mudita Singhal, ...
103
Voted
FGCS
2006
144views more  FGCS 2006»
15 years 25 days ago
BioSimGrid: Grid-enabled biomolecular simulation data storage and analysis
In computational biomolecular research, large amounts of simulation data are generated to capture the motion of proteins. These massive simulation data can be analysed in a number...
Muan Hong Ng, Steven Johnston, Bing Wu, Stuart E. ...
94
Voted
BMCBI
2007
123views more  BMCBI 2007»
15 years 25 days ago
Normalization and experimental design for ChIP-chip data
Background: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. ...
Shouyong Peng, Artyom A. Alekseyenko, Erica Larsch...
120
Voted
NAR
2011
248views Computer Vision» more  NAR 2011»
14 years 3 months ago
NCBI GEO: archive for functional genomics data sets - 10 years on
A decade ago, the Gene Expression Omnibus (GEO) database was established at the National Center for Biotechnology Information (NCBI). The original objective of GEO was to serve as...
Tanya Barrett, Dennis B. Troup, Stephen E. Wilhite...