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BMCBI
2007
122views more  BMCBI 2007»
15 years 14 days ago
TAP score: torsion angle propensity normalization applied to local protein structure evaluation
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
Silvio C. E. Tosatto, Roberto Battistutta
95
Voted
IPPS
2006
IEEE
15 years 6 months ago
A method to improve structural modeling based on conserved domain clusters
—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Fa Zhang, Lin Xu, Bo Yuan
97
Voted
GECCO
2003
Springer
165views Optimization» more  GECCO 2003»
15 years 5 months ago
An Evolutionary Approach for Molecular Docking
We have developed an evolutionary approach for the flexible docking that is now an important component of a rational drug design. This automatic docking tool, referred to as the G...
Jinn-Moon Yang
92
Voted
BMCBI
2010
86views more  BMCBI 2010»
15 years 15 days ago
Mining protein loops using a structural alphabet and statistical exceptionality
Background: Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, ca...
Leslie Regad, Juliette Martin, Grégory Nuel...
103
Voted
MLMTA
2007
15 years 1 months ago
Prediction of Protein Secondary Structures with a Novel Kernel Density Estimator
- Though prediction of protein secondary structures has been an active research issue in bioinformatics for quite a few years and many approaches have been proposed, a new challeng...
Yen-Jen Oyang, Darby Tien-Hao Chang, Yu-Yen Ou, Ha...