Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
The organization and mining of malaria genomic and post-genomic data is important to significantly increase the knowledge of the biology of its causative agents, and is motivated,...
L.-M. Birkholtz, Olivier Bastien, G. Wells, D. Gra...
Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...