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152
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BMCBI
2011
14 years 8 months ago
Implementation of Force Distribution Analysis for Molecular Dynamics simulations
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
Wolfram Stacklies, Christian Seifert, Frauke Graet...
NAR
2011
233views Computer Vision» more  NAR 2011»
14 years 3 months ago
ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures
ArachnoServer (www.arachnoserver.org) is a manually curated database providing information on the sequence, structure and biological activity of protein toxins from spider venoms....
Volker Herzig, David L. A. Wood, Felicity Newell, ...
118
Voted
BMCBI
2007
141views more  BMCBI 2007»
15 years 1 months ago
A novel approach to detect hot-spots in large-scale multivariate data
Background: Progressive advances in the measurement of complex multifactorial components of biological processes involving both spatial and temporal domains have made it difficult...
Jianhua Wu, Keith M. Kendrick, Jianfeng Feng
BMCBI
2008
184views more  BMCBI 2008»
15 years 18 days ago
"TOF2H": A precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI
Background: Protein-amide proton hydrogen-deuterium exchange (HDX) is used to investigate protein conformation, conformational changes and surface binding sites for other molecule...
Pornpat Nikamanon, Elroy Pun, Wayne Chou, Marek D....
BMCBI
2008
103views more  BMCBI 2008»
15 years 1 months ago
Parameter estimation for robust HMM analysis of ChIP-chip data
Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
Peter Humburg, David Bulger, Glenn Stone