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BMCBI
2011
14 years 2 months ago
PeakRanger: A cloud-enabled peak caller for ChIP-seq data
Background: Chromatin immunoprecipitation (ChIP), coupled with massively parallel short-read sequencing (seq) is used to probe chromatin dynamics. Although there are many algorith...
Xin Feng, Robert Grossman, Lincoln Stein
WILF
2007
Springer
170views Fuzzy Logic» more  WILF 2007»
15 years 4 months ago
Time-Series Alignment by Non-negative Multiple Generalized Canonical Correlation Analysis
Background: Quantitative analysis of differential protein expressions requires to align temporal elution measurements from liquid chromatography coupled to mass spectrometry (LC/M...
Bernd Fischer, Volker Roth, Joachim M. Buhmann
COMPLIFE
2006
Springer
15 years 2 months ago
Beating the Noise: New Statistical Methods for Detecting Signals in MALDI-TOF Spectra Below Noise Level
Background: The computer-assisted detection of small molecules by mass spectrometry in biological samples provides a snapshot of thousands of peptides, protein fragments and prote...
Tim O. F. Conrad, Alexander Leichtle, Andre Hageh&...
BMCBI
2010
145views more  BMCBI 2010»
14 years 10 months ago
WaveletQuant, an improved quantification software based on wavelet signal threshold de-noising for labeled quantitative proteomi
Background: Quantitative proteomics technologies have been developed to comprehensively identify and quantify proteins in two or more complex samples. Quantitative proteomics base...
Fan Mo, Qun Mo, Yuanyuan Chen, David R. Goodlett, ...
BMCBI
2007
167views more  BMCBI 2007»
14 years 10 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...