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ICCS
2007
Springer
15 years 4 months ago
A Multiscale, Cell-Based Framework for Modeling Cancer Development
We use a systems approach to develop a predictive model that medical researchers can use to study and treat cancerous tumors. Our multiscale, cell-based model includes intracellula...
Yi Jiang
87
Voted
CSB
2003
IEEE
111views Bioinformatics» more  CSB 2003»
15 years 3 months ago
A Contradiction-Based Framework for Testing Gene Regulation Hypotheses
We have developed a mathematical framework for representing and testing hypotheses about gene, protein, and signaling molecule interactions. It takes a hierarchical, contradiction...
Steve Racunas, Nigam Shah, Nina V. Fedoroff
GCB
1997
Springer
77views Biometrics» more  GCB 1997»
15 years 2 months ago
Statistics of large scale sequence searching
Motivation: Database search programs such as FASTA, BLAST or a rigorous Smith–Waterman algorithm produce lists of database entries, which are assumed to be related to the query....
Rainer Spang, Martin Vingron
ICANN
2007
Springer
15 years 2 months ago
Neural Network Approach for Mass Spectrometry Prediction by Peptide Prototyping
In todays bioinformatics, Mass spectrometry (MS) is the key technique for the identification of proteins. A prediction of spectrum peak intensities from pre computed molecular feat...
Alexandra Scherbart, Wiebke Timm, Sebastian Bö...
AUSAI
2008
Springer
15 years 10 days ago
Propositionalisation of Profile Hidden Markov Models for Biological Sequence Analysis
Hidden Markov Models are a widely used generative model for analysing sequence data. A variant, Profile Hidden Markov Models are a special case used in Bioinformatics to represent,...
Stefan Mutter, Bernhard Pfahringer, Geoffrey Holme...