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113
Voted
BMCBI
2010
14 years 10 months ago
2010
Background: Minimotifs are short peptide sequences within one protein, which are recognized by other proteins or molecules. While there are now several minimotif databases, they a...
BMCBI
2010
2010
On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence
14 years 10 months ago
Background: In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput gen...
BMCBI
2010
14 years 10 months ago
2010
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
BMCBI
2008
14 years 10 months ago
2008
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
81
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...