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NAR
2010
123views more  NAR 2010»
14 years 4 months ago
Discovering causal signaling pathways through gene-expression patterns
High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant members...
Jignesh R. Parikh, Bertram Klinger, Yu Xia, Jarrod...
RECOMB
2004
Springer
15 years 10 months ago
Modeling and Analysis of Heterogeneous Regulation in Biological Networks
Abstract. In this study we propose a novel model for the representation of biological networks and provide algorithms for learning model parameters from experimental data. Our appr...
Irit Gat-Viks, Amos Tanay, Ron Shamir
ISMB
2007
15 years 11 days ago
A Chado case study: an ontology-based modular schema for representing genome-associated biological information
Motivation: A few years ago, FlyBase undertook to design a new database schema to store Drosophila data. It would fully integrate genomic sequence and annotation data with bibliog...
Chris Mungall, David B. Emmert
SDM
2004
SIAM
211views Data Mining» more  SDM 2004»
14 years 11 months ago
Using Support Vector Machines for Classifying Large Sets of Multi-Represented Objects
Databases are a key technology for molecular biology which is a very data intensive discipline. Since molecular biological databases are rather heterogeneous, unification and data...
Hans-Peter Kriegel, Peer Kröger, Alexey Pryak...
BIODATAMINING
2008
117views more  BIODATAMINING 2008»
14 years 10 months ago
Search extension transforms Wiki into a relational system: A case for flavonoid metabolite database
Background: In computer science, database systems are based on the relational model founded by Edgar Codd in 1970. On the other hand, in the area of biology the word 'databas...
Masanori Arita, Kazuhiro Suwa