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BMCBI
2007
154views more  BMCBI 2007»
14 years 10 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
JCB
2007
198views more  JCB 2007»
14 years 10 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
NAR
2007
155views more  NAR 2007»
14 years 9 months ago
Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research
Frequent outbreaks of highly pathogenic avian influenza and the increasing data available for comparative analysis require a central database specialized in influenza viruses (IVs...
Suhua Chang, Jiajie Zhang, Xiaoyun Liao, Xinxing Z...
BMCBI
2011
14 years 5 months ago
Shape-based peak identification for ChIP-Seq
Background: The identification of binding targets for proteins using ChIP-Seq has gained popularity as an alternative to ChIP-chip. Sequencing can, in principle, eliminate artifac...
Valerie Hower, Steven N. Evans, Lior Pachter
BMCBI
2011
14 years 1 months ago
RegNetB: Predicting Relevant Regulator-Gene Relationships in Localized Prostate Tumor Samples
Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Angel Alvarez, Peter J. Woolf