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» The Protein Data Bank
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GCC
2006
Springer
15 years 4 months ago
Grid Enabled Data Integration Framework for Bioinformatics Research
A framework is proposed to manage the distributed and heterogeneous databases in grid environment for understanding protein-protein interaction. Furthermore, the framework is used...
Jia Liu, Yongwei Wu, Weimin Zheng
85
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PSB
2004
15 years 2 months ago
Motif Discovery in Heterogeneous Sequence Data
This paper introduces the first integrated algorithm designed to discover novel motifs in heterogeneous sequence data, which is comprised of coregulated genes from a single genome...
Amol Prakash, Mathieu Blanchette, Saurabh Sinha, M...
74
Voted
BMCBI
2006
59views more  BMCBI 2006»
15 years 20 days ago
Novel methods for secondary structure determination using low wavelength (VUV) circular dichroism spectroscopic data
Background: Circular Dichroism (CD) spectroscopy is a widely used method for studying protein structures in solution. Modern synchrotron radiation CD (SRCD) instruments have consi...
Jonathan G. Lees, Andrew J. Miles, Robert W. Janes...
BMCBI
2007
141views more  BMCBI 2007»
15 years 22 days ago
Reconstruction of human protein interolog network using evolutionary conserved network
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
Tao-Wei Huang, Chung-Yen Lin, Cheng-Yan Kao
165
Voted
BMCBI
2007
265views more  BMCBI 2007»
15 years 22 days ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...