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» The Rise and Rise of Citation Analysis
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90
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BMCBI
2010
89views more  BMCBI 2010»
14 years 10 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...
BMCBI
2010
181views more  BMCBI 2010»
14 years 10 months ago
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
Amit Zeisel, Amnon Amir, Wolfgang J. Köstler,...
83
Voted
BMCBI
2008
145views more  BMCBI 2008»
14 years 10 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
CONSTRAINTS
2006
77views more  CONSTRAINTS 2006»
14 years 10 months ago
The Impact of Search Heuristics on Heavy-Tailed Behaviour
Abstract. The heavy-tailed phenomenon that characterises the runtime distributions of backtrack search procedures has received considerable attention over the past few years. Some ...
Tudor Hulubei, Barry O'Sullivan
BMCBI
2007
187views more  BMCBI 2007»
14 years 10 months ago
BioWMS: a web-based Workflow Management System for bioinformatics
Background: An in-silico experiment can be naturally specified as a workflow of activities implementing, in a standardized environment, the process of data and control analysis. A...
Ezio Bartocci, Flavio Corradini, Emanuela Merelli,...