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» The Robustness of Level Sets
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99
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BMCBI
2010
104views more  BMCBI 2010»
15 years 28 days ago
A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative th
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
Yunqi Li, C. Russell Middaugh, Jianwen Fang
104
Voted
BMCBI
2010
183views more  BMCBI 2010»
15 years 28 days ago
SOPRA: Scaffolding algorithm for paired reads via statistical optimization
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
Adel Dayarian, Todd P. Michael, Anirvan M. Sengupt...
103
Voted
BMCBI
2010
144views more  BMCBI 2010»
15 years 28 days ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...
120
Voted
BMCBI
2008
140views more  BMCBI 2008»
15 years 28 days ago
FUNYBASE: a FUNgal phYlogenomic dataBASE
Background: The increasing availability of fungal genome sequences provides large numbers of proteins for evolutionary and phylogenetic analyses. However the heterogeneity of data...
Sylvain Marthey, Gabriela Aguileta, Françoi...
106
Voted
BMCBI
2008
96views more  BMCBI 2008»
15 years 28 days ago
Use of normalization methods for analysis of microarrays containing a high degree of gene effects
Background: High-throughput microarrays are widely used to study gene expression across tissues and developmental stages. Analysis of gene expression data is challenging in these ...
Terri T. Ni, William J. Lemon, Yu Shyr, Tao P. Zho...
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