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» The Robustness of Level Sets
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103
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BMCBI
2005
89views more  BMCBI 2005»
15 years 17 days ago
Theme discovery from gene lists for identification and viewing of multiple functional groups
Background: High throughput methods of the genome era produce vast amounts of data in the form of gene lists. These lists are large and difficult to interpret without advanced com...
Petri Pehkonen, Garry Wong, Petri Töröne...
117
Voted
BMCBI
2005
152views more  BMCBI 2005»
15 years 17 days ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
96
Voted
BMCBI
2005
104views more  BMCBI 2005»
15 years 17 days ago
An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer i
Background: Neoplastic transformation is a multistep process in which distinct gene products of specific cell regulatory pathways are involved at each stage. Identification of ove...
Federica Cavallo, Annalisa Astolfi, Manuela Iezzi,...
103
Voted
MANSCI
2007
86views more  MANSCI 2007»
15 years 16 days ago
Proper Conditioning for Coherent VaR in Portfolio Management
Value at Risk (VaR) is a central concept in risk management. As stressed by Artzner et al. (1999), VaR may not possess the subadditivity property required to be a coherent measure...
René Garcia, Éric Renault, Georges T...
BMCBI
2004
169views more  BMCBI 2004»
15 years 16 days ago
A power law global error model for the identification of differentially expressed genes in microarray data
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...
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