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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
15 years 15 days ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2006
88views more  BMCBI 2006»
15 years 15 days ago
A two-sample Bayesian t-test for microarray data
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...
Richard J. Fox, Matthew W. Dimmic
123
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BMCBI
2006
174views more  BMCBI 2006»
15 years 15 days ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...
113
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BMCBI
2006
99views more  BMCBI 2006»
15 years 15 days ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2006
128views more  BMCBI 2006»
15 years 15 days ago
An interactive tool for visualization of relationships between gene expression profiles
Background: Application of phenetic methods to gene expression analysis proved to be a successful approach. Visualizing the results in a 3-dimentional space may further enhance th...
Peter Ruzanov, Steven J. M. Jones
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