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» The SUPERFAMILY database in 2007: families and functions
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BMCBI
2007
120views more  BMCBI 2007»
14 years 9 months ago
Quantitative sequence-function relationships in proteins based on gene ontology
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
Vineet Sangar, Daniel J. Blankenberg, Naomi Altman...
CIDR
2007
165views Algorithms» more  CIDR 2007»
14 years 11 months ago
A Black-Box Approach to Query Cardinality Estimation
We present a “black-box” approach to estimating query cardinality that has no knowledge of query execution plans and data distribution, yet provides accurate estimates. It doe...
Tanu Malik, Randal C. Burns, Nitesh V. Chawla
BMCBI
2007
107views more  BMCBI 2007»
14 years 9 months ago
Reuse of structural domain-domain interactions in protein networks
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
Benjamin Schuster-Böckler, Alex Bateman
BMCBI
2007
175views more  BMCBI 2007»
14 years 9 months ago
CLUSS: Clustering of protein sequences based on a new similarity measure
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...
BMCBI
2006
114views more  BMCBI 2006»
14 years 9 months ago
Taxonomic colouring of phylogenetic trees of protein sequences
Background: Phylogenetic analyses of protein families are used to define the evolutionary relationships between homologous proteins. The interpretation of protein-sequence phyloge...
Gareth Palidwor, Emmanuel G. Reynaud, Miguel A. An...