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BMCBI
2007
130views more  BMCBI 2007»
15 years 2 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BMCBI
2010
50views more  BMCBI 2010»
15 years 2 months ago
Scanner calibration revisited
Background: Calibration of a microarray scanner is critical for accurate interpretation of microarray results. Shi et al. (BMC Bioinformatics, 2005, 6, Art. No. S11 Suppl. 2.) rep...
Alexander E. Pozhitkov
BMCBI
2008
108views more  BMCBI 2008»
15 years 2 months ago
SPRINT: A new parallel framework for R
Background: Microarray analysis allows the simultaneous measurement of thousands to millions of genes or sequences across tens to thousands of different samples. The analysis of t...
Jon Hill, Matthew Hambley, Thorsten Forster, Murie...
BMCBI
2007
104views more  BMCBI 2007»
15 years 2 months ago
A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and de
Background: Yu et al. (BMC Bioinformatics 2007,8: 145+) have recently compared the performance of several methods for the detection of genomic amplification and deletion breakpoin...
Oscar M. Rueda, Ramón Díaz-Uriarte
BMCBI
2010
176views more  BMCBI 2010»
14 years 12 months ago
Haplotype association analyses in resources of mixed structure using Monte Carlo testing
Background: Genomewide association studies have resulted in a great many genomic regions that are likely to harbor disease genes. Thorough interrogation of these specific regions ...
Ryan Abo, Jathine Wong, Alun Thomas, Nicola J. Cam...