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BMCBI
2010
185views more  BMCBI 2010»
14 years 11 months ago
ABCtoolbox: a versatile toolkit for approximate Bayesian computations
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
Daniel Wegmann, Christoph Leuenberger, Samuel Neue...
BMCBI
2010
89views more  BMCBI 2010»
14 years 11 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...
BMCBI
2008
99views more  BMCBI 2008»
14 years 11 months ago
A new real-time PCR method to overcome significant quantitative inaccuracy due to slight amplification inhibition
Background: Real-time PCR analysis is a sensitive DNA quantification technique that has recently gained considerable attention in biotechnology, microbiology and molecular diagnos...
Michele Guescini, Davide Sisti, Marco B. L. Rocchi...
CORR
2010
Springer
109views Education» more  CORR 2010»
14 years 11 months ago
Polynomial Learning of Distribution Families
Abstract--The question of polynomial learnability of probability distributions, particularly Gaussian mixture distributions, has recently received significant attention in theoreti...
Mikhail Belkin, Kaushik Sinha
DATAMINE
2008
143views more  DATAMINE 2008»
14 years 11 months ago
Automatically countering imbalance and its empirical relationship to cost
Learning from imbalanced datasets presents a convoluted problem both from the modeling and cost standpoints. In particular, when a class is of great interest but occurs relatively...
Nitesh V. Chawla, David A. Cieslak, Lawrence O. Ha...